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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
PSMD9_HUMAN
USC-OGP 2-DE database
:
PSMD9_HUMAN
PSMD9_HUMAN
General information about the entry
View entry in simple text format
Entry name
PSMD9_HUMAN
Primary accession number
O00233
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=26S proteasome non-ATPase regulatory subunit 9; AltName: Full=26S proteasome regulatory subunit p27;.
Gene name
Name=PSMD9
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0499
:
pI=6.32; Mw=28351
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1286
:
pI=6.01; Mw=25688
Cross-references
UniProtKB/Swiss-Prot
O00233; PSMD9_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PSMD9_HUMAN
Primary accession number
O00233
Secondary accession number(s)
B2RD35 G3V1Q6 Q9BQ42
Sequence was last modified on
January 11, 2011 (version 3)
Annotations were last modified on
March 15, 2017 (version 164)
Name and origin of the protein
Description
RecName: Full=26S proteasome non-ATPase regulatory subunit 9; AltName: Full=26S proteasome regulatory subunit p27;
Gene name
Name=PSMD9
Encoded on
Name=PSMD9
Keywords
Alternative splicing
;
Chaperone
;
Complete proteome
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AB003177; BAA19790.1
; -; mRNA
EMBL
AK315389; BAG37782.1
; -; mRNA
EMBL
CB111716; -
; NOT_ANNOTATED_CDS; mRNA
EMBL
AC069503; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471054; EAW98296.1
; -; Genomic_DNA
EMBL
BC002383; AAH02383.1
; -; mRNA
EMBL
BC004184; AAH04184.1
; -; mRNA
EMBL
BC004213; AAH04213.1
; -; mRNA
CCDS
CCDS58284.1; -. [O00233-3]
; .
CCDS
CCDS9225.1; -. [O00233-1]
; .
RefSeq
NP_001248329.1; NM_001261400.2. [O00233-3]
; .
RefSeq
NP_002804.2; NM_002813.6. [O00233-1]
; .
UniGene
Hs.131151; -
; .
ProteinModelPortal
O00233; -
; .
SMR
O00233; -
; .
BioGrid
111687; 67
; .
IntAct
O00233; 17
; .
MINT
MINT-1435362; -
; .
STRING
9606.ENSP00000440485; -
; .
iPTMnet
O00233; -
; .
PhosphoSitePlus
O00233; -
; .
BioMuta
PSMD9; -
; .
OGP
O00233; -
; .
EPD
O00233; -
; .
MaxQB
O00233; -
; .
PaxDb
O00233; -
; .
PeptideAtlas
O00233; -
; .
PRIDE
O00233; -
; .
TopDownProteomics
O00233-1; -. [O00233-1]
; .
DNASU
5715; -
; .
Ensembl
ENST00000537407; ENSP00000445058
; ENSG00000110801. [O00233-2]; .
Ensembl
ENST00000541212; ENSP00000440485
; ENSG00000110801. [O00233-1]; .
Ensembl
ENST00000542602; ENSP00000443772
; ENSG00000110801. [O00233-3]; .
GeneID
5715; -
; .
KEGG
hsa:5715; -
; .
UCSC
uc001ubl.5; human. [O00233-1]
; .
CTD
5715; -
; .
DisGeNET
5715; -
; .
GeneCards
PSMD9; -
; .
HGNC
HGNC:9567; PSMD9
; .
HPA
HPA040512; -
; .
HPA
HPA044220; -
; .
MIM
603146; gene
; .
neXtProt
NX_O00233; -
; .
OpenTargets
ENSG00000110801; -
; .
PharmGKB
PA33913; -
; .
eggNOG
KOG3129; Eukaryota
; .
eggNOG
COG0265; LUCA
; .
GeneTree
ENSGT00390000004147; -
; .
HOGENOM
HOG000216665; -
; .
HOVERGEN
HBG001851; -
; .
InParanoid
O00233; -
; .
KO
K06693; -
; .
OMA
LGCNIVP; -
; .
OrthoDB
EOG091G0N53; -
; .
PhylomeDB
O00233; -
; .
TreeFam
TF105995; -
; .
Reactome
R-HSA-1169091; Activation of NF-kappaB in B cells
; .
Reactome
R-HSA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
; .
Reactome
R-HSA-1236974; ER-Phagosome pathway
; .
Reactome
R-HSA-1236978; Cross-presentation of soluble exogenous antigens (endosomes)
; .
Reactome
R-HSA-174084; Autodegradation of Cdh1 by Cdh1:APC/C
; .
Reactome
R-HSA-174113; SCF-beta-TrCP mediated degradation of Emi1
; .
Reactome
R-HSA-174154; APC/C:Cdc20 mediated degradation of Securin
; .
Reactome
R-HSA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
; .
Reactome
R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A
; .
Reactome
R-HSA-180534; Vpu mediated degradation of CD4
; .
Reactome
R-HSA-180585; Vif-mediated degradation of APOBEC3G
; .
Reactome
R-HSA-187577; SCF(Skp2)-mediated degradation of p27/p21
; .
Reactome
R-HSA-195253; Degradation of beta-catenin by the destruction complex
; .
Reactome
R-HSA-202424; Downstream TCR signaling
; .
Reactome
R-HSA-211733; Regulation of activated PAK-2p34 by proteasome mediated degradation
; .
Reactome
R-HSA-2467813; Separation of Sister Chromatids
; .
Reactome
R-HSA-2871837; FCERI mediated NF-kB activation
; .
Reactome
R-HSA-349425; Autodegradation of the E3 ubiquitin ligase COP1
; .
Reactome
R-HSA-350562; Regulation of ornithine decarboxylase (ODC)
; .
Reactome
R-HSA-382556; ABC-family proteins mediated transport
; .
Reactome
R-HSA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA
; .
Reactome
R-HSA-4608870; Asymmetric localization of PCP proteins
; .
Reactome
R-HSA-4641257; Degradation of AXIN
; .
Reactome
R-HSA-4641258; Degradation of DVL
; .
Reactome
R-HSA-5358346; Hedgehog ligand biogenesis
; .
Reactome
R-HSA-5362768; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
; .
Reactome
R-HSA-5607761; Dectin-1 mediated noncanonical NF-kB signaling
; .
Reactome
R-HSA-5607764; CLEC7A (Dectin-1) signaling
; .
Reactome
R-HSA-5610780; Degradation of GLI1 by the proteasome
; .
Reactome
R-HSA-5610783; Degradation of GLI2 by the proteasome
; .
Reactome
R-HSA-5610785; GLI3 is processed to GLI3R by the proteasome
; .
Reactome
R-HSA-5632684; Hedgehog 'on' state
; .
Reactome
R-HSA-5658442; Regulation of RAS by GAPs
; .
Reactome
R-HSA-5668541; TNFR2 non-canonical NF-kB pathway
; .
Reactome
R-HSA-5676590; NIK-->noncanonical NF-kB signaling
; .
Reactome
R-HSA-5678895; Defective CFTR causes cystic fibrosis
; .
Reactome
R-HSA-5687128; MAPK6/MAPK4 signaling
; .
Reactome
R-HSA-5689603; UCH proteinases
; .
Reactome
R-HSA-5689880; Ub-specific processing proteases
; .
Reactome
R-HSA-68827; CDT1 association with the CDC6:ORC:origin complex
; .
Reactome
R-HSA-68949; Orc1 removal from chromatin
; .
Reactome
R-HSA-69017; CDK-mediated phosphorylation and removal of Cdc6
; .
Reactome
R-HSA-69229; Ubiquitin-dependent degradation of Cyclin D1
; .
Reactome
R-HSA-69481; G2/M Checkpoints
; .
Reactome
R-HSA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
; .
Reactome
R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint
; .
Reactome
R-HSA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
; .
Reactome
R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation
; .
GeneWiki
PSMD9; -
; .
GenomeRNAi
5715; -
; .
PRO
PR:O00233; -
; .
Proteomes
UP000005640; Chromosome 12
; .
Bgee
ENSG00000110801; -
; .
CleanEx
HS_PSMD9; -
; .
ExpressionAtlas
O00233; baseline and differential
; .
Genevisible
O00233; HS
; .
GO
GO:0005737; C:cytoplasm
; IBA:GO_Central; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0005654; C:nucleoplasm
; TAS:Reactome; .
GO
GO:0005634; C:nucleus
; ISS:BHF-UCL; .
GO
GO:0005838; C:proteasome regulatory particle
; NAS:UniProtKB; .
GO
GO:0043425; F:bHLH transcription factor binding
; ISS:BHF-UCL; .
GO
GO:0003713; F:transcription coactivator activity
; ISS:BHF-UCL; .
GO
GO:0031145; P:anaphase-promoting complex-dependent catabolic process
; TAS:Reactome; .
GO
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I
; TAP-dependent; TAS:Reactome
GO
GO:0038095; P:Fc-epsilon receptor signaling pathway
; TAS:Reactome; .
GO
GO:0000165; P:MAPK cascade
; TAS:Reactome; .
GO
GO:0090090; P:negative regulation of canonical Wnt signaling pathway
; TAS:Reactome; .
GO
GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle
; TAS:Reactome; .
GO
GO:0046676; P:negative regulation of insulin secretion
; ISS:BHF-UCL; .
GO
GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
; TAS:Reactome; .
GO
GO:0038061; P:NIK/NF-kappaB signaling
; TAS:Reactome; .
GO
GO:0090263; P:positive regulation of canonical Wnt signaling pathway
; TAS:Reactome; .
GO
GO:0032024; P:positive regulation of insulin secretion
; ISS:BHF-UCL; .
GO
GO:0045893; P:positive regulation of transcription
; DNA-templated; ISS:BHF-UCL
GO
GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
; TAS:Reactome; .
GO
GO:0070682; P:proteasome regulatory particle assembly
; IMP:UniProtKB; .
GO
GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process
; TAS:Reactome; .
GO
GO:0016579; P:protein deubiquitination
; TAS:Reactome; .
GO
GO:0000209; P:protein polyubiquitination
; TAS:Reactome; .
GO
GO:0006521; P:regulation of cellular amino acid metabolic process
; TAS:Reactome; .
GO
GO:0043488; P:regulation of mRNA stability
; TAS:Reactome; .
GO
GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia
; TAS:Reactome; .
GO
GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
; TAS:Reactome; .
GO
GO:0002223; P:stimulatory C-type lectin receptor signaling pathway
; TAS:Reactome; .
GO
GO:0050852; P:T cell receptor signaling pathway
; TAS:Reactome; .
GO
GO:0055085; P:transmembrane transport
; TAS:Reactome; .
GO
GO:0033209; P:tumor necrosis factor-mediated signaling pathway
; TAS:Reactome; .
GO
GO:0006511; P:ubiquitin-dependent protein catabolic process
; NAS:UniProtKB; .
GO
GO:0060071; P:Wnt signaling pathway
; planar cell polarity pathway; TAS:Reactome
Gene3D
2.30.42.10; -
; 1; .
InterPro
IPR001478; PDZ
; .
Pfam
PF13180; PDZ_2
; 1; .
SMART
SM00228; PDZ
; 1; .
SUPFAM
SSF50156; SSF50156
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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